Description

3-Quinolinecarboxylic Acid, 7-[4-[(5-Chloro-2-Thienyl)Carbonyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, structurally complex organic compound designed for advanced chemical synthesis. This molecule is of significant interest in pharmaceutical research and development, particularly as a key intermediate or precursor in the creation of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable access to high-quality, specialized building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel quinolone and fluoroquinolone-based antibiotic candidates.
• Active Pharmaceutical Ingredient (API) Research: Used in the research and development of new therapeutic agents targeting bacterial infections.
• Chemical Biology & Medicinal Chemistry: Employed as a scaffold or precursor for creating compound libraries to study structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Provides a defined starting material for optimizing synthetic routes and scaling up production of target molecules.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Custom Synthesis & Contract Manufacturing: A key material for fine chemical manufacturers offering bespoke synthesis services to the pharma industry.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 7-[4-[(5-Chloro-2-Thienyl)Carbonyl]-1-Piperazinyl]-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1054010-30-8
Molecular Formula	C22H19ClFN3O4S
Molecular Weight	475.92 g/mol
Synonyms	7-[4-[(5-Chloro-2-thienyl)carbonyl]-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-7-[4-[(5-chloro-2-thienyl)carbonyl]-1-piperazinyl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-((5-chlorothiophene-2-carbonyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; GSK-2140944 Intermediate; GSK2140944 Intermediate; GSK 2140944 Precursor; 1054010-30-8
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.