Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-(2-Methylbenzoyl)-1-Piperazinyl]-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the synthesis of novel fluoroquinolone antibiotics, offering a key building block for research and development in antimicrobial therapies. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers focused on active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of next-generation fluoroquinolone antibiotic candidates.
• Antimicrobial Research: Serves as a core scaffold for developing new antibacterial agents targeting resistant bacterial strains.
• Chemical Synthesis: Used in organic synthesis for constructing complex quinoline-based molecular architectures.
• API Development: Employed in the process development and scale-up manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Research: Utilized in studies investigating structure-activity relationships (SAR) of antibacterial compounds.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-7-[4-(2-Methylbenzoyl)-1-Piperazinyl]-4-Oxo-
CAS No.	1054009-66-3
Molecular Formula	C25H24FN3O4
Molecular Weight	449.48 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-7-[4-(2-methylbenzoyl)-1-piperazinyl]-4-oxo-3-quinolinecarboxylic acid; 7-[4-(2-Methylbenzoyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; Garenoxacin Intermediate; Garenoxacin Carboxylic Acid Derivative; 1-Cyclopropyl-6-fluoro-7-(4-(2-methylbenzoyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; AM-1155 Intermediate; OPC-17116 Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific pharmacopeial or internal standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if necessary and opened only in a moisture-controlled environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.