Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-(Cyclopropylcarbonyl)-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is a key synthetic precursor in the development of novel antimicrobial agents, particularly within the fluoroquinolone class. It is essential for pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and new drug discovery. The material is supplied to meet the stringent quality requirements of the global life sciences industry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of next-generation fluoroquinolone antibiotics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and the development of new antimicrobial candidates.
• Fine Chemical Synthesis: Serves as a versatile precursor for the preparation of more complex, functionalized quinoline derivatives.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis and pharmacology.
• Reference Standard: Suitable for use as a high-purity analytical standard for quality control and method development.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-(Cyclopropylcarbonyl)-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1053952-42-3
Molecular Formula	C21H22FN3O4
Molecular Weight	399.42 g/mol
Synonyms	1-Cyclopropyl-7-[4-(cyclopropylcarbonyl)piperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-(cyclopropanecarbonyl)piperazin-1-yl)quinoline-3-carboxylic Acid; 7-[4-(Cyclopropylcarbonyl)-1-piperazinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid; WCK 771 Intermediate; Levonadifloxacin Intermediate; Advanced Fluoroquinolone Intermediate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure compliance with pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.