Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-(3,5-Dimethylbenzoyl)-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is primarily targeted at research institutions, custom synthesis houses, and large-scale pharmaceutical manufacturers engaged in the development and production of next-generation antibacterial agents.

Application

• Key Intermediate for Antibiotic Synthesis: Serves as a crucial building block in the multi-step synthesis of potent fluoroquinolone antibiotics.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new antibacterial candidates.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling up production processes for target APIs.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules and clinical trial materials.
• Reference Standard: Can be utilized as a high-purity analytical standard for quality control and regulatory submissions.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-(3,5-Dimethylbenzoyl)-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1053950-72-3
Molecular Formula	C26H25FN3O3
Molecular Weight	446.50 g/mol
Synonyms	1-Cyclopropyl-7-[4-(3,5-dimethylbenzoyl)piperazin-1-yl]-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-7-(4-(3,5-dimethylbenzoyl)piperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; WCK 771 Intermediate; Levonadifloxacin Intermediate; Benzonaphthyridine Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and reliability. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.