Description

2,4-Dichloro-5-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its molecular structure, featuring halogenated pyrimidine and pyrrole rings, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of kinase inhibitors and other targeted small-molecule drugs.
• Agrochemical Research: Used in the development of new herbicides and fungicides with specific modes of action.
• Material Science: Acts as a building block for creating specialty polymers and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Contract Research & Manufacturing (CRO/CMO): A vital raw material for custom synthesis and scale-up projects.

Basic Information

Product Name	2,4-Dichloro-5-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine
CAS No.	1053228-29-7
Molecular Formula	C6H2Cl2FN3
Molecular Weight	205.00 g/mol
Synonyms	2,4-Dichloro-5-fluoro-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine, 2,4-dichloro-5-fluoro-; 5-Fluoro-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Dichloro-5-fluoropyrrolo[2,3-d]pyrimidine; Fluoropyrrolopyrimidine derivative; Halogenated pyrrolopyrimidine
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-Fluoro-7H-Pyrrolo[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light). For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.