Description

5-Amino-2-Chloropyrimidine-4-Carboxylic Acid is a high-purity pyrimidine derivative building block essential for advanced organic synthesis. This compound matters as a versatile precursor in the development of active pharmaceutical ingredients (APIs), particularly for antiviral and anticancer agents. It is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel nucleoside analogs and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides and fungicides with pyrimidine-based structures.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization (e.g., amidation, esterification) to create diverse chemical libraries.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic materials.
• Bioconjugation: The carboxylic acid group enables coupling reactions for creating labeled probes or protein conjugates in biochemical research.

Basic Information

Product Name	5-Amino-2-Chloropyrimidine-4-Carboxylic Acid
CAS No.	1052714-41-6
Molecular Formula	C5H4ClN3O2
Molecular Weight	173.56 g/mol
Synonyms	2-Chloro-5-aminopyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 5-amino-2-chloro-; 5-Amino-2-chloro-4-pyrimidinecarboxylic acid; 2-Chloro-5-amino-4-pyrimidinecarboxylic acid; ACPCA; 5-Amino-2-chloropyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Chloropyrimidine-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.