Description

5-Bromo-2-Fluoroaniline Hydrochloride is a high-purity, halogenated aniline derivative essential for advanced organic synthesis. This compound serves as a critical building block in the development of active pharmaceutical ingredients (APIs) and sophisticated agrochemicals, where its unique halogen substitution pattern enables precise molecular modifications. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic systems and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides that require specific halogenated aniline motifs for enhanced activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reagent for labeling and modifying biomolecules, facilitating studies in drug discovery and diagnostic assay development.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized azo dyes and pigments with improved lightfastness and color properties.

Basic Information

Product Name	5-Bromo-2-Fluoroaniline Hydrochloride
CAS No.	1052403-50-5
Molecular Formula	C6H6BrClFN
Molecular Weight	226.47 g/mol
Synonyms	2-Fluoro-5-bromoaniline hydrochloride; 5-Bromo-2-fluoroaniline HCl; 5-Bromo-2-fluoroaniline monohydrochloride; 2-Fluoro-5-bromobenzenamine hydrochloride; Benzenamine, 5-bromo-2-fluoro-, hydrochloride (1:1); 5-Bromo-2-fluoro-phenylamine hydrochloride; 1-Amino-5-bromo-2-fluorobenzene hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluoroaniline Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) for every shipment, supporting compliance with cGMP and ICH Q7 guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.