Description

4-(3-Fluorophenyl)-3-Fluorophenol is a high-purity fluorinated phenolic compound, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique bifluorinated aromatic structure, which is essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, where the fluorinated phenol moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated monomers used in electronic display materials, contributing to improved performance and durability.
• Polymer Modification: Acts as a functional monomer or chain terminator in the production of specialty engineering plastics with enhanced thermal and chemical resistance.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a protecting group precursor in complex multi-step syntheses.
• Chemical Research & Development: A valuable tool compound in academic and industrial labs for exploring new fluorination chemistry and structure-activity relationships (SAR).

Basic Information

Product Name	4-(3-Fluorophenyl)-3-Fluorophenol
CAS No.	1052241-69-6
Molecular Formula	C12H8F2O
Molecular Weight	206.19 g/mol
Synonyms	3-Fluoro-4-(3-fluorophenyl)phenol; 4-(3-Fluorophenyl)-3-fluorophenol; 1,1'-Biphenyl-3,4'-diol, 3',4-difluoro-; 3',4-Difluoro-[1,1'-biphenyl]-3,4'-diol; 3-(3-Fluorophenyl)-4-fluorophenol; [1,1'-Biphenyl]-3,4'-diol, 3',4-difluoro-; Difluorobiphenyldiol
EINECS	Contact for details

Quality Control

Our 4-(3-Fluorophenyl)-3-Fluorophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent oxidation or degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.