Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-7-[4-(1-Oxopentyl)-1-Piperazinyl]- is a high-purity advanced pharmaceutical intermediate (API intermediate) with a complex heterocyclic structure. This compound is critical for the synthesis of next-generation fluoroquinolone antibiotics, offering a key building block for research and development. It is primarily required by pharmaceutical manufacturers, R&D laboratories, and fine chemical suppliers focused on antimicrobial drug development and production.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel fluoroquinolone antibiotic active pharmaceutical ingredients (APIs).
• Antimicrobial Research: Used in medicinal chemistry for developing new antibacterial agents with improved efficacy and spectrum.
• Process Chemistry: Serves as a critical raw material in scale-up and commercial manufacturing processes for antibiotic drugs.
• Fine Chemical Synthesis: Employed in the preparation of complex, multi-functionalized quinoline derivatives for various biological studies.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) specializing in potent and complex molecules.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-7-[4-(1-Oxopentyl)-1-Piperazinyl]-
CAS No.	1051329-81-7
Molecular Formula	C22H26FN3O4
Molecular Weight	415.46 g/mol
Synonyms	1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[4-(1-oxopentyl)-1-piperazinyl]-3-quinolinecarboxylic acid; 7-(4-Valeryl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; Garenoxacin Intermediate; Garenoxacin Quinoline Core; AM-1155 Intermediate; T-3811 Intermediate; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-pentanoyl-1-piperazinyl)-; 7-(4-Pentanoylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid derivative is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.