Description

3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(4-Ethyl-5-Methyl-2-Thienyl)Carbonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting antibacterial and anti-infective drug discovery programs.

Application

• Key Intermediate in Antibacterial Drug Synthesis: Serves as a crucial building block for the development of next-generation quinolone and fluoroquinolone antibiotics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and pharmacokinetic properties of new chemical entities.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and pre-clinical development of novel drugs.
• Academic Research: Utilized in university and institutional labs for biochemical and pharmacological studies targeting bacterial enzymes.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[4-[(4-Ethyl-5-Methyl-2-Thienyl)Carbonyl]-1-Piperazinyl]-6-Fluoro-1,4-Dihydro-4-Oxo-
CAS No.	1051248-85-1
Molecular Formula	C24H24FN3O4S
Molecular Weight	469.53 g/mol
Synonyms	1-Cyclopropyl-7-[4-[(4-ethyl-5-methyl-2-thienyl)carbonyl]-1-piperazinyl]-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(4-[(4-ethyl-5-methyl-2-thienyl)carbonyl]-1-piperazinyl)-3-quinolinecarboxylic Acid; WCK 771; WCK-771; WCK771; (Advanced Fluoroquinolone Intermediate); Contact for additional aliases.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for pharmaceutical R&D. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and MS. We support development under cGMP guidelines where required, ensuring traceability and documentation for regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.