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2-Fluoro-6-Methoxy-Phenylamine Hydrochloride CAS NO 1049790-78-4


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CAS No.:1049790-78-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Fluoro-6-Methoxy-Phenylamine Hydrochloride is a high-purity organic building block essential for advanced chemical synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and sophisticated agrochemicals, where its specific fluorine and methoxy substitution pattern enables precise molecular design. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and other therapeutic areas.
  • Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
  • Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and other functional materials requiring specific aromatic amine structures.
  • Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
  • Academic and Industrial R&D: Used in research laboratories for method development, exploring new chemical reactions, and creating compound libraries for screening.

Basic Information

Product Name 2-Fluoro-6-Methoxy-Phenylamine Hydrochloride
CAS No. 1049790-78-4
Molecular Formula C7H9ClFNO
Molecular Weight 177.60 g/mol
Synonyms 2-Fluoro-6-methoxyaniline hydrochloride; 2-Fluoro-6-methoxybenzenamine hydrochloride; 1-Amino-2-fluoro-6-methoxybenzene hydrochloride; 2-Amino-3-fluoroanisole hydrochloride; 6-Methoxy-2-fluoroaniline HCl; 2-Fluoro-6-methoxyphenylamine HCl; 2-Fluoro-6-methoxy-phenylamine hydrochloride
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Quality Control

Our 2-Fluoro-6-Methoxy-Phenylamine Hydrochloride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliable supply for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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