Description

4'-Fluorobiphenyl-2-Ylamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in medicinal chemistry and materials science. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biphenyl scaffold for bioactivity.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials, such as those for OLEDs and semiconductors, due to its conjugated biphenyl structure.
• Chemical Biology & Proteomics: Utilized as a scaffold or linker in the design of molecular probes and tools for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	4'-Fluorobiphenyl-2-Ylamine Hydrochloride
CAS No.	1049733-12-1
Molecular Formula	C12H10FN•HCl
Molecular Weight	223.67 g/mol (Free base: 187.22 g/mol)
Synonyms	2-Amino-4'-fluorobiphenyl Hydrochloride; 4'-Fluoro[1,1'-biphenyl]-2-amine Hydrochloride; 2-(4-Fluorophenyl)aniline Hydrochloride; 4-Fluorobiphenyl-2-ylamine HCl; 2-Amino-4'-fluorodiphenyl Hydrochloride; 4'-Fluoro-2-biphenylamine Hydrochloride; (4-Fluorophenyl)(2-aminophenyl)methane Hydrochloride
EINECS	Contact for details

Quality Control

Our 4'-Fluorobiphenyl-2-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, residual solvents, and heavy metals are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.