Description

1-Naphthylacetyl Spermine Trihydrochloride is a chemically modified polyamine derivative of significant interest in biochemical and pharmacological research. This compound matters as a valuable tool compound for studying polyamine transport, metabolism, and their roles in cellular processes, particularly in relation to cancer biology. Researchers in the fields of medicinal chemistry, molecular biology, and oncology need it for developing novel therapeutic strategies and diagnostic probes.

Application

• Biochemical Research: Used as a molecular probe to study polyamine uptake mechanisms and intracellular trafficking in various cell lines.
• Medicinal Chemistry: Serves as a key intermediate or reference standard in the synthesis and development of novel polyamine-based therapeutics targeting hyperproliferative diseases.
• Oncology Studies: Employed in in vitro and in vivo experiments to investigate the role of polyamine analogs in modulating tumor growth and apoptosis.
• Enzyme Inhibition Assays: Acts as a potential substrate or inhibitor for enzymes involved in polyamine metabolism, such as spermidine/spermine N1-acetyltransferase (SSAT).
• Diagnostic Agent Development: Explored for the creation of labeled conjugates for imaging applications, leveraging the naphthyl moiety for fluorescence or radio-labeling.

Basic Information

Product Name	1-Naphthylacetyl Spermine Trihydrochloride
CAS No.	1049731-36-3
Molecular Formula	C26H41Cl3N4O
Molecular Weight	532.0 g/mol (approx.)
Synonyms	N1-(1-Naphthylacetyl)spermine trihydrochloride; N1-(1-Naphthylacetyl)spermine trihydrochloride; 1-Naphthaleneacetic acid, N-[4-[[4-[(3-aminopropyl)amino]butyl]amino]butyl]-, trihydrochloride; Spermine, N1-(1-naphthylacetyl)-, trihydrochloride; N1-(1-Naphthylacetyl)spermine 3HCl; N1-(1-Naphthaleneacetyl)spermine trihydrochloride
EINECS	Contact for details

Quality Control

Our 1-Naphthylacetyl Spermine Trihydrochloride is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.