Description

4-(N,N-Dimethylamino)-3,5-Bis(trifluoromethyl)aniline is a high-value, multi-functional aromatic amine intermediate featuring a dimethylamino group and two electron-withdrawing trifluoromethyl substituents. This unique structure makes it a critical building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where specific electronic and steric properties are required. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to develop novel compounds with enhanced bioactivity and stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups improve lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science: Incorporated into the synthesis of advanced polymers, dyes, and liquid crystals to modify electronic properties and solubility.
• Organic Electronics: Potential building block for charge-transport materials or emissive layers in OLEDs and other electronic devices.
• Chemical Research: A versatile reagent for academic and industrial R&D in medicinal chemistry and synthetic methodology development.

Basic Information

Product Name	4-(N,N-Dimethylamino)-3,5-Bis(trifluoromethyl)aniline
CAS No.	1048915-57-6
Molecular Formula	C11H10F6N2
Molecular Weight	284.20 g/mol
Synonyms	3,5-Bis(trifluoromethyl)-4-(dimethylamino)aniline; 4-(Dimethylamino)-3,5-bis(trifluoromethyl)benzenamine; 4-(Dimethylamino)-3,5-bis(trifluoromethyl)aniline; 4-Amino-2,6-bis(trifluoromethyl)-N,N-dimethylaniline; N,N-Dimethyl-3,5-bis(trifluoromethyl)-1,4-benzenediamine; 1048915-57-6; 3,5-Bis(trifluoromethyl)-4-(N,N-dimethylamino)aniline
EINECS	Contact for details

Quality Control

Our production of 4-(N,N-Dimethylamino)-3,5-Bis(trifluoromethyl)aniline adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.