Description

1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl methanesulfonate is a high-purity organic intermediate of significant importance in advanced chemical synthesis. This compound serves as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of new-generation pesticides and herbicides requiring specific pyrimidine-based structures.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Chemistry: Employed in route scouting and optimization for the commercial manufacturing of target compounds.
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API production.

Basic Information

Product Name	1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl methanesulfonate
CAS No.	1046817-01-9
Molecular Formula	C13H21N3O3S
Molecular Weight	299.39 g/mol
Synonyms	1-(5-Ethyl-2-pyrimidinyl)-4-piperidinyl methanesulfonate; 4-Piperidinol, 1-(5-ethyl-2-pyrimidinyl)-, methanesulfonate (ester); UNII-1J3P8Q5T6F; 1J3P8Q5T6F; Methanesulfonic acid, 1-(5-ethyl-2-pyrimidinyl)-4-piperidinyl ester; 1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl mesylate
EINECS	Contact for details

Quality Control

Our 1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl methanesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.