Description

3-(1-(5-Ethylpyrimidin-2-Yl)Piperdin-4-Yl)Propan-L-Ol (Synonyms: 4-Pyrimidylpiperidinepropanol) is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of next-generation therapeutics. The product is supplied under stringent quality control to ensure batch-to-batch consistency for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a core scaffold or a functionalized fragment in the production of investigational and commercial APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Biochemical Research: Utilized as a tool compound or a ligand in biochemical assays and pharmacological studies.
• Fine Chemical Production: Employed in the manufacture of other specialized, high-value nitrogen-containing heterocycles.

Basic Information

Product Name	3-(1-(5-Ethylpyrimidin-2-Yl)Piperdin-4-Yl)Propan-L-Ol
CAS No.	1046815-82-0
Molecular Formula	C14H23N3O
Molecular Weight	249.35 g/mol
Synonyms	4-Pyrimidylpiperidinepropanol; 3-[1-(5-Ethyl-2-pyrimidinyl)-4-piperidinyl]-1-propanol; 1-Propanol, 3-[1-(5-ethyl-2-pyrimidinyl)-4-piperidinyl]-; 3-(1-(5-Ethylpyrimidin-2-yl)piperidin-4-yl)propan-1-ol; 5-Ethyl-2-(4-(3-hydroxypropyl)piperidin-1-yl)pyrimidine; 4-(3-Hydroxypropyl)-1-(5-ethylpyrimidin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our 3-(1-(5-Ethylpyrimidin-2-Yl)Piperdin-4-Yl)Propan-L-Ol is manufactured and tested under a strict quality management system. Each batch is analyzed to meet exacting standards for identity, purity, and impurity profile, suitable for demanding pharmaceutical R&D applications. Certificates of Analysis (COA) detailing comprehensive analytical results from HPLC, NMR, and MS are provided with every shipment. We support compliance with cGMP and ISO 9001 guidelines for research-grade materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.