Description

4-Chloro-5-Fluoro-2-(Methoxymethyl)Pyrimidine is a high-value, multi-functional pyrimidine derivative that serves as a critical building block in advanced organic synthesis. Its molecular structure, featuring chloro, fluoro, and methoxymethyl substituents, makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent synthesis.
• Agrochemical Synthesis: Used as a precursor for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Research: A versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for various industrial applications.
• Material Science: Potential building block for the synthesis of organic electronic materials and liquid crystals.

Basic Information

Product Name	4-Chloro-5-Fluoro-2-(Methoxymethyl)Pyrimidine
CAS No.	1046788-84-4
Molecular Formula	C6H6ClFN2O
Molecular Weight	176.57 g/mol
Synonyms	2-(Methoxymethyl)-4-chloro-5-fluoropyrimidine; 4-Chloro-5-fluoro-2-methoxymethylpyrimidine; 4-Chloro-5-fluoro-2-(methoxymethyl)pyrimidine; Pyrimidine, 4-chloro-5-fluoro-2-(methoxymethyl)-; 1046788-84-4
EINECS	Contact for details

Quality Control

Our 4-Chloro-5-Fluoro-2-(Methoxymethyl)Pyrimidine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.