Description

4-Chloro-2-Cyclopropylpyrimidine is a high-purity pyrimidine derivative, a crucial halogenated heterocyclic building block in advanced organic synthesis. Its core value lies in enabling the efficient construction of complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce the cyclopropylpyrimidine scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and insecticides with the cyclopropylpyrimidine moiety.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands, organic semiconductors, and liquid crystal materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	4-Chloro-2-Cyclopropylpyrimidine
CAS No.	1044771-74-5
Molecular Formula	C7H7ClN2
Molecular Weight	154.60 g/mol
Synonyms	2-Cyclopropyl-4-chloropyrimidine; 4-Chloro-2-cyclopropyl-pyrimidine; Pyrimidine, 4-chloro-2-cyclopropyl-; 4-Chloro-2-cyclopropylpyrimidine; 1044771-74-5
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Cyclopropylpyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring reliable and consistent raw material supply for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.