Description

Ethyl 2-Cyclopropyl-6-Oxo-1,6-Dihydropyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1044770-39-9. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), valued for its precise molecular structure that enables targeted drug development. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of novel therapeutic agents.

Application

This specialized intermediate serves as a key precursor in several high-value chemical synthesis pathways. Its primary applications include:

• Pharmaceutical Intermediate: Core building block for the synthesis of novel drug candidates, particularly in antiviral and anticancer research.
• Organic Synthesis Research: Used in academic and industrial R&D for constructing complex heterocyclic compounds and studying reaction mechanisms.
• Agrochemical Development: Serves as a precursor in the research and synthesis of new-generation pesticides and herbicides.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the cGMP production of clinical trial materials and commercial APIs.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 2-Cyclopropyl-6-Oxo-1,6-Dihydropyrimidine-5-Carboxylate
CAS No.	1044770-39-9
Molecular Formula	C10H12N2O3
Molecular Weight	208.21 g/mol
Synonyms	Ethyl 2-cyclopropyl-6-oxo-1,6-dihydropyrimidine-5-carboxylate; 5-Pyrimidinecarboxylic acid, 2-cyclopropyl-1,6-dihydro-6-oxo-, ethyl ester; 2-Cyclopropyl-6-oxo-1,6-dihydropyrimidine-5-carboxylic acid ethyl ester; 1044770-39-9; Ethyl 2-cyclopropyl-6-oxo-1H-pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Cyclopropyl-6-Oxo-1,6-Dihydropyrimidine-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.