Description

4-Chloro-2-Methyl-5-Nitropyrimidine is a versatile and high-value heterocyclic building block, essential for advanced organic synthesis. Its core value lies in its reactive chloro and nitro substituents, which enable precise functionalization for creating complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Research & Development: Serves as a versatile scaffold for exploring new chemical entities and reaction pathways in medicinal chemistry.
• Material Science: Potential building block for creating specialized polymers, ligands, or organic electronic materials.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring functionalized pyrimidine cores.

Basic Information

Product Name	4-Chloro-2-Methyl-5-Nitropyrimidine
CAS No.	1044768-00-4
Molecular Formula	C5H4ClN3O2
Molecular Weight	173.56 g/mol
Synonyms	5-Nitro-2-methyl-4-chloropyrimidine; 2-Methyl-4-chloro-5-nitropyrimidine; 4-Chloro-2-methyl-5-nitro-pyrimidine; 4-Chloro-2-methyl-5-nitropyrimidine; 2-Methyl-4-chloro-5-nitro-1,3-diazine; Pyrimidine, 4-chloro-2-methyl-5-nitro-; 1044768-00-4 (CAS)
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Methyl-5-Nitropyrimidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.