Description

5-Bromo-4-Chloropyrimidin-2-Amine is a high-purity halogenated pyrimidine building block, essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its specific halogen substitution pattern enables precise molecular modifications. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides.
• Chemical Research: Serves as a versatile building block in medicinal chemistry and process development for structure-activity relationship (SAR) studies.
• Material Science: Potential use in the development of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	5-Bromo-4-Chloropyrimidin-2-Amine
CAS No.	1044767-99-8
Molecular Formula	C4H4BrClN3
Molecular Weight	208.45 g/mol
Synonyms	2-Amino-5-bromo-4-chloropyrimidine; 4-Chloro-5-bromopyrimidin-2-amine; 5-Bromo-4-chloro-2-pyrimidinamine; 4-Chloro-5-bromo-2-aminopyrimidine; 2-Pyrimidinamine, 5-bromo-4-chloro-; 5-Bromo-4-chloro-2-aminopyrimidine; 5-Bromo-4-chloro-pyrimidin-2-ylamine
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Chloropyrimidin-2-Amine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.