Description

2-Fluoro-6-(Trifluoromethyl)-Dl-Phenylalanine is a fluorinated, non-natural amino acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and trifluoromethyl groups, is engineered to modulate the physicochemical properties and metabolic stability of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced potency and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in protease inhibitor and oncology research.
• Peptidomimetics & Bioactive Peptides: Incorporated into peptide chains to enhance stability against enzymatic degradation and improve membrane permeability.
• Agrochemical Research: Used in the synthesis of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Chemical Biology Probes: Serves as a building block for fluorescent tags or affinity probes to study protein interactions and enzyme mechanisms.
• Material Science: Potential monomer or modifier for specialty polymers where fluorine content imparts desirable properties like hydrophobicity or chemical resistance.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	2-Fluoro-6-(Trifluoromethyl)-Dl-Phenylalanine
CAS No.	1043500-58-8
Molecular Formula	C₁₀H₉F₄NO₂
Molecular Weight	251.18 g/mol
Synonyms	DL-2-Fluoro-6-(trifluoromethyl)phenylalanine; (RS)-2-Amino-3-[2-fluoro-6-(trifluoromethyl)phenyl]propanoic acid; 2-Fluoro-6-trifluoromethyl-DL-phenylalanine; 2-Fluoro-α-methyl-6-(trifluoromethyl)benzenepropanoic acid; F-Tfm-Phe; 2-F-6-CF3-DL-Phe; α-Amino-2-fluoro-6-trifluoromethylhydrocinnamic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Trifluoromethyl)-Dl-Phenylalanine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profile is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.