Description

4-(3-Bromophenoxy)-3-Fluoroaniline is a specialized aromatic amine derivative featuring bromophenoxy and fluoroaniline functional groups. This compound serves as a high-value pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecules for advanced research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific halogenated aromatic motifs into their target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, where the bromo and fluoro substituents can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Biology Probes: Useful for synthesizing fluorescent tags or molecular probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(3-Bromophenoxy)-3-Fluoroaniline
CAS No.	1039920-66-5
Molecular Formula	C12H9BrFNO
Molecular Weight	282.11 g/mol
Synonyms	3-Fluoro-4-(3-bromophenoxy)aniline; 4-(3-Bromophenoxy)-3-fluoro-benzenamine; 1-(3-Bromophenoxy)-2-fluoro-4-aminobenzene; Benzenamine, 4-(3-bromophenoxy)-3-fluoro-; 3'-Bromo-3-fluoro-4-aminodiphenyl ether
EINECS	Contact for details

Quality Control

Our 4-(3-Bromophenoxy)-3-Fluoroaniline is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.