Description

(1R)-4,4',6,6'-Tetrakis(Trifluoromethyl)-[1,1'-Biphenyl]-2,2'-Diamine is a high-value, chiral biphenyl derivative distinguished by its four trifluoromethyl groups, which confer unique electronic and steric properties. This compound is critical for applications requiring precise molecular recognition and stability under demanding conditions, such as in advanced materials and pharmaceutical synthesis. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for use as a sophisticated building block or chiral ligand.

Application

• As a chiral ligand or catalyst in asymmetric synthesis for pharmaceutical intermediates.
• As a key building block in the development of novel active pharmaceutical ingredients (APIs).
• In the research and synthesis of advanced organic electronic materials, such as OLEDs or semiconductors, due to its electron-withdrawing trifluoromethyl groups.
• For the development of specialty agrochemicals requiring specific stereochemistry and environmental stability.
• As a molecular scaffold in supramolecular chemistry and materials science research.
• In analytical chemistry as a reference standard or reagent for method development and quality control.

Basic Information

Product Name	(1R)-4,4',6,6'-Tetrakis(Trifluoromethyl)-[1,1'-Biphenyl]-2,2'-Diamine
CAS No.	1037800-51-3
Molecular Formula	C₁₆H₆F₁₂N₂
Molecular Weight	502.22 g/mol
Synonyms	(R)-4,4',6,6'-Tetrakis(trifluoromethyl)biphenyl-2,2'-diamine; (1R)-4,4',6,6'-Tetrakis(trifluoromethyl)-2,2'-diaminobiphenyl; (R)-TFBDA; (R)-Tetrafluoromethyl Biphenyl Diamine; 2,2'-Diamino-4,4',6,6'-tetrakis(trifluoromethyl)-1,1'-biphenyl, (R)-; (R)-Perfluorinated Biphenyl Diamine Derivative
EINECS	Contact for details

Quality Control

Our (1R)-4,4',6,6'-Tetrakis(Trifluoromethyl)-[1,1'-Biphenyl]-2,2'-Diamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.