Description

[3-Fluoro-4-(2-Methyl-1H-Imidazol-1-Yl)Phenyl]Methanamine is a high-value, functionalized aromatic amine building block featuring a fluorine substituent and a methylimidazole moiety. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, enabling the introduction of specific pharmacophores that influence bioactivity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine and heterocyclic groups can enhance biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials requiring specific electronic or binding properties.
• Bioconjugation and Probe Chemistry: The primary amine group allows for conjugation, making it useful for creating fluorescent probes or biochemical tools.
• Chemical Library Synthesis: A valuable building block for constructing diverse compound libraries in high-throughput screening and medicinal chemistry programs.

Basic Information

Product Name	[3-Fluoro-4-(2-Methyl-1H-Imidazol-1-Yl)Phenyl]Methanamine
CAS No.	1037163-76-0
Molecular Formula	C11H12FN3
Molecular Weight	205.23 g/mol
Synonyms	1-(4-(Aminomethyl)-2-fluorophenyl)-2-methyl-1H-imidazole; (3-Fluoro-4-(2-methyl-1H-imidazol-1-yl)phenyl)methanamine; 4-(Aminomethyl)-2-fluoro-1-(2-methyl-1H-imidazol-1-yl)benzene; 1-[4-(Aminomethyl)-2-fluorophenyl]-2-methylimidazole; 1037163-76-0; FC-IMZ-AM; Benzenemethanamine, 3-fluoro-4-(2-methyl-1H-imidazol-1-yl)-
EINECS	Contact for details

Quality Control

Our [3-Fluoro-4-(2-Methyl-1H-Imidazol-1-Yl)Phenyl]Methanamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment aligns with cGMP standards where required, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.