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Acth (3-24) (Human, Bovine, Rat) CAS NO 1036763-00-4
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CAS No.:1036763-00-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Acth (3-24) (Human, Bovine, Rat) is a synthetic peptide fragment of the adrenocorticotropic hormone (ACTH), a key regulator of the adrenal cortex. This high-purity reference standard is critical for ensuring the accuracy and reliability of research and diagnostic assays in endocrinology. It is primarily utilized by pharmaceutical R&D teams, clinical diagnostics laboratories, and academic researchers focused on adrenal function and stress response studies. The compound is supplied with full analytical documentation to support rigorous quality requirements.
Application
- Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods (e.g., HPLC, LC-MS) in drug development and quality control.
- Biomedical Research: Serves as a critical reagent in studies investigating the structure, function, and signaling pathways of ACTH and related peptides.
- Clinical Diagnostics: Employed as a calibrator or control material in immunoassays (ELISA, RIA) for the quantitative measurement of ACTH levels in patient samples.
- Endocrinology Studies: Facilitates research into adrenal gland disorders, Cushing's syndrome, Addison's disease, and the physiological stress response.
- Peptide Chemistry & Synthesis: Acts as a building block or intermediate for the synthesis of longer, modified ACTH analogs for therapeutic exploration.
Basic Information
| Product Name | Acth (3-24) (Human, Bovine, Rat) |
| CAS No. | 1036763-00-4 |
| Molecular Formula | C112H168N32O31S |
| Molecular Weight | 2467.8 g/mol |
| Synonyms | ACTH (3-24); Adrenocorticotropic Hormone Fragment 3-24; Corticotropin (3-24); H-Val-Gly-Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asp-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe-OH; Tetracosactide fragment 3-24; Synacthen fragment 3-24 |
| EINECS | Contact for details |
Quality Control
Every batch of Acth (3-24) is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC) | Retention time corresponds to reference standard |
| Identification (MS) | Mass spectrum confirms molecular weight |
| Purity (HPLC) | ≥ 95.0% |
| Peptide Content | ≥ 80.0% (by weight) |
| Water Content (KF) | ≤ 5.0% |
| Acetate Content (HPIC) | ≤ 10.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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