Description

2(1H)-Quinazolinone, 6-Bromo-8-Fluoro- is a high-purity, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinazolinone scaffold, functionalized with bromo and fluoro substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in kinase inhibitor and anticancer agent discovery.
• Agrochemical Research: Used in the synthesis of new herbicides, fungicides, and pesticides, leveraging the bioactivity of the quinazolinone core.
• Chemical Biology Probe: Serves as a building block for creating molecular probes to study biological pathways and enzyme functions.
• Material Science Research: Potential precursor for the development of specialty chemicals and advanced organic materials.
• Academic & Contract Research: Employed in universities and CROs (Contract Research Organizations) for methodological studies and library synthesis.

Basic Information

Product Name	2(1H)-Quinazolinone, 6-Bromo-8-Fluoro-
CAS No.	1036756-15-6
Molecular Formula	C8H4BrFN2O
Molecular Weight	243.04 g/mol
Synonyms	6-Bromo-8-fluoroquinazolin-2(1H)-one; 6-Bromo-8-fluoro-1,2-dihydroquinazolin-2-one; 6-Bromo-8-fluoro-2-hydroxyquinazoline; 8-Fluoro-6-bromo-2(1H)-quinazolinone; 1036756-15-6; 6-Bromo-8-fluoroquinazolinone
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinazolinone, 6-Bromo-8-Fluoro- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.