Description

6-Quinazolinecarboxylic Acid, 1,2-Dihydro-2-Oxo-, Methyl Ester is a high-purity, synthetically valuable heterocyclic building block. This compound serves as a critical intermediate in the development of novel pharmaceutical agents, particularly in medicinal chemistry research. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and agrochemical sectors for synthesizing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of quinazoline-based drug candidates, including kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, fungicides, or plant growth regulators containing the quinazoline moiety.
• Organic Synthesis Building Block: Utilized in academic and industrial laboratories for constructing complex heterocyclic compounds due to its reactive ester and carbonyl functionalities.
• Biochemical Tool Compound: May be used in the development of biochemical probes for studying enzyme mechanisms or cellular pathways.

Basic Information

Product Name	6-Quinazolinecarboxylic Acid, 1,2-Dihydro-2-Oxo-, Methyl Ester
CAS No.	1036755-95-9
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	Methyl 1,2-dihydro-2-oxoquinazoline-6-carboxylate; Methyl 2-oxo-1,2-dihydroquinazoline-6-carboxylate; 2-Oxo-1,2-dihydroquinazoline-6-carboxylic acid methyl ester; 1,2-Dihydro-2-oxoquinazoline-6-carboxylic Acid Methyl Ester; Quinazoline-6-carboxylic acid, 1,2-dihydro-2-oxo-, methyl ester; 6-(Methoxycarbonyl)-1,2-dihydroquinazolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Quinazolinecarboxylic Acid, 1,2-Dihydro-2-Oxo-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.