Description

2(1H)-Quinazolinone, 6-Bromo-8-Chloro- is a high-purity, halogenated quinazolinone derivative, a crucial heterocyclic building block in advanced organic synthesis. Its core value lies in its functionalized structure, which serves as a versatile scaffold for constructing complex molecules with targeted biological or material properties. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, particularly for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs or charge-transport layers, due to its conjugated system.
• Chemical Biology: Employed as a molecular probe or a tag in biochemical assays and proteomics research.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling and heterocyclic chemistry.
• Custom Synthesis: Used by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex heterocycles.

Basic Information

Product Name	2(1H)-Quinazolinone, 6-Bromo-8-Chloro-
CAS No.	1036755-78-8
Molecular Formula	C8H4BrClN2O
Molecular Weight	259.49 g/mol
Synonyms	6-Bromo-8-chloro-1,2-dihydroquinazolin-2-one; 6-Bromo-8-chloro-2(1H)-quinazolinone; 8-Chloro-6-bromo-1,2-dihydroquinazolin-2-one; 8-Chloro-6-bromo-2(1H)-quinazolinone; 6-Bromo-8-chloro-2-quinazolinone; 6-Bromo-8-chloro-1H-quinazolin-2-one; Quinazolin-2(1H)-one, 6-bromo-8-chloro-
EINECS	Contact for details

Quality Control

Our 2(1H)-Quinazolinone, 6-Bromo-8-Chloro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.