Description

Ethyl 4-(4-Fluorophenyl)-6-Isopropyl-2-(n-Methylsulfonamido)Pyrimidine-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex pyrimidine-based molecular structure. This compound is critical for ensuring the quality and consistency of downstream active pharmaceutical ingredients (APIs) in regulated manufacturing processes. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development and synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly in medicinal chemistry research and development.
• API Synthesis: Used in the production route for Active Pharmaceutical Ingredients (APIs) targeting various therapeutic areas.
• Chemical Research: Serves as a valuable substrate for method development, structure-activity relationship (SAR) studies, and novel compound library generation.
• Preclinical Development: Employed in the scale-up synthesis of candidate compounds for toxicology and pharmacokinetic studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.

Basic Information

Product Name	Ethyl 4-(4-Fluorophenyl)-6-Isopropyl-2-(n-Methylsulfonamido)Pyrimidine-5-Carboxylate
CAS No.	1035595-71-1
Molecular Formula	C17H20FN3O4S
Molecular Weight	381.42 g/mol
Synonyms	Ethyl 4-(4-fluorophenyl)-6-isopropyl-2-[(methylsulfonyl)amino]pyrimidine-5-carboxylate; 2-(N-Methylsulfonamido)-4-(4-fluorophenyl)-6-isopropyl-5-pyrimidinecarboxylic Acid Ethyl Ester; 1035595-71-1; 4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylsulfonylamino)pyrimidine-5-carboxylic acid ethyl ester; Ethyl 4-(p-fluorophenyl)-6-isopropyl-2-(N-methylsulfonylamino)pyrimidine-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(4-Fluorophenyl)-6-Isopropyl-2-(n-Methylsulfonamido)Pyrimidine-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.