Description

2-Chloro-4-Methyl-6-Piperidin-4-Yl-Pyrimidine is a high-purity, functionalized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile synthetic intermediate for constructing complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research for central nervous system (CNS) and other therapeutic areas.
• Agrochemical Research: Used in the development and synthesis of new pesticides and herbicides, leveraging its heterocyclic core structure.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, enzyme inhibitors, and other tools for biological target identification and validation.
• Material Science: Potential intermediate in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials.
• Contract Research & Development (CRO/CMO): Supplied to organizations requiring custom synthesis and scale-up services for client projects.
• Academic Research: Used in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	2-Chloro-4-Methyl-6-Piperidin-4-Yl-Pyrimidine
CAS No.	1035453-19-0
Molecular Formula	C10H14ClN3
Molecular Weight	211.69 g/mol
Synonyms	2-Chloro-4-methyl-6-(piperidin-4-yl)pyrimidine; 4-(2-Chloro-4-methylpyrimidin-6-yl)piperidine; 6-Piperidin-4-yl-2-chloro-4-methylpyrimidine; 2-Chloro-4-methyl-6-(4-piperidinyl)pyrimidine; 1035453-19-0; 2-Chloro-4-methyl-6-(piperidin-4-yl)-pyrimidine; 4-(2-Chloro-4-methyl-6-pyrimidinyl)piperidine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-4-Methyl-6-Piperidin-4-Yl-Pyrimidine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade meets a typical purity specification of ≥95% (by HPLC). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key parameters such as assay, impurity profile, and residual solvents. We support custom synthesis to meet specific purity requirements (e.g., ≥98% or ≥99%) for advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.