Description

(2-Methylpyrimidin-5-Yl)Boronic Acid is a high-value boronic acid derivative and a key synthetic building block in modern organic chemistry. Its primary importance lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific pyrimidine-based scaffolds.
• Material Science: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the development of molecular probes and sensors due to its specific binding affinity.
• Academic & Contract Research: A valuable reagent for method development and exploratory synthesis in university and CRO laboratories.
• Ligand Synthesis: Used to prepare sophisticated ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	(2-Methylpyrimidin-5-Yl)Boronic Acid
CAS No.	1034924-06-5
Molecular Formula	C5H7BN2O2
Molecular Weight	137.94 g/mol
Synonyms	5-(2-Methylpyrimidin-5-yl)boronic acid; (2-Methyl-5-pyrimidinyl)boronic acid; 2-Methylpyrimidine-5-boronic acid; 2-Methyl-5-pyrimidineboronic acid; B-(2-Methyl-5-pyrimidinyl)boronic acid; 5-Borono-2-methylpyrimidine; 1034924-06-5; (2-Methylpyrimidin-5-yl)boronic acid pinacol ester (common derivative)
EINECS	Contact for details

Quality Control

Our (2-Methylpyrimidin-5-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We support compliance with relevant industry standards for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.