Description

Methyl 2-Amino-5-Bromopyrimidine-4-Carboxylate is a high-purity brominated pyrimidine derivative, a crucial advanced intermediate in modern organic synthesis. This compound is valued for its reactive bromine and ester functional groups, which enable precise molecular construction in complex chemical pathways. It is primarily required by pharmaceutical R&D and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialized materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides that require specific pyrimidine scaffolds.
• Material Science Research: Serves as a precursor for creating functionalized organic molecules used in electronic materials or liquid crystals.
• Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring bromo-substituted heterocycles.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical reactions.

Basic Information

Product Name	Methyl 2-Amino-5-Bromopyrimidine-4-Carboxylate
CAS No.	1034737-23-9
Molecular Formula	C6H6BrN3O2
Molecular Weight	232.04 g/mol
Synonyms	Methyl 5-Bromo-2-aminopyrimidine-4-carboxylate; 2-Amino-5-bromopyrimidine-4-carboxylic acid methyl ester; 5-Bromo-2-aminopyrimidine-4-carboxylic acid methyl ester; Methyl 2-amino-5-bromo-4-pyrimidinecarboxylate; 4-Pyrimidinecarboxylic acid, 2-amino-5-bromo-, methyl ester; 1034737-23-9
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5-Bromopyrimidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.