Description

(R)-1-(4-Chloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Phenyl)-2,2,2-Trifluoroethanol is a high-value chiral trifluoromethylated alcohol building block of significant interest in advanced organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals due to the unique properties imparted by its stereochemistry and fluorine atoms. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for creating enantiomerically pure target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of new drug candidates, particularly in areas requiring high stereochemical purity.
• Agrochemical Development: Used in the creation of advanced, enantiomerically pure pesticides and herbicides where specific stereochemistry enhances efficacy and reduces environmental impact.
• Asymmetric Synthesis: Serves as a versatile building block in catalytic asymmetric reactions to construct complex molecular architectures.
• Ligand and Catalyst Precursor: Can be utilized in the development of novel chiral ligands or organocatalysts for synthetic chemistry applications.
• Material Science Research: Potential precursor for specialty polymers or advanced materials incorporating fluorine for unique thermal or chemical resistance properties.

Basic Information

Product Name	(R)-1-(4-Chloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Phenyl)-2,2,2-Trifluoroethanol
CAS No.	1033805-26-3
Molecular Formula	C12H10ClF3N2O
Molecular Weight	290.67 g/mol
Synonyms	(R)-1-[4-Chloro-2-(3-methyl-1H-pyrazol-1-yl)phenyl]-2,2,2-trifluoroethanol; (R)-1-(4-Chloro-2-(3-methylpyrazol-1-yl)phenyl)-2,2,2-trifluoroethanol; (R)-4-Chloro-2-(3-methyl-1H-pyrazol-1-yl)-α-(trifluoromethyl)benzyl alcohol; (R)-α-(Trifluoromethyl)-4-chloro-2-(3-methyl-1H-pyrazol-1-yl)benzenemethanol; CAS 1033805-26-3
EINECS	Contact for details

Quality Control

Our (R)-1-(4-Chloro-2-(3-Methyl-1H-Pyrazol-1-Yl)Phenyl)-2,2,2-Trifluoroethanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.