Description

L-Phenylalanine, 4-(2-Amino-6-Chloro-4-Pyrimidinyl)-n-[(1,1-Dimethylethoxy)Carbonyl]- is a sophisticated, non-natural amino acid derivative designed for advanced pharmaceutical research and development. This compound serves as a critical building block in the synthesis of complex peptides and bioactive molecules, offering precise structural control for medicinal chemists. It is primarily utilized by R&D teams in the pharmaceutical and biotechnology sectors for the development of new therapeutic agents, including protease inhibitors and targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and investigational new drugs.
• Peptide Synthesis: Used as a modified amino acid residue in solid-phase and solution-phase peptide synthesis to introduce specific functionality.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the design of enzyme inhibitors or receptor modulators.
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Chemical Biology Probes: Utilized to create labeled or tagged compounds for studying biological pathways and protein interactions.
• Process Development: Supports scale-up and optimization of synthetic routes for potential commercial manufacturing.

Basic Information

Product Name	L-Phenylalanine, 4-(2-Amino-6-Chloro-4-Pyrimidinyl)-n-[(1,1-Dimethylethoxy)Carbonyl]-
CAS No.	1033804-86-2
Molecular Formula	C18H22ClN5O4
Molecular Weight	407.85 g/mol
Synonyms	Boc-4-(2-Amino-6-chloro-4-pyrimidinyl)-L-phenylalanine; (2S)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-3-[4-(2-amino-6-chloropyrimidin-4-yl)phenyl]propanoic acid; N-Boc-4-(2-Amino-6-chloro-pyrimidin-4-yl)-L-phenylalanine; 4-(2-Amino-6-chloro-4-pyrimidinyl)-N-(tert-butoxycarbonyl)-L-phenylalanine; N-(tert-Butoxycarbonyl)-4-(2-amino-6-chloro-4-pyrimidinyl)-L-phenylalanine; Boc-Phe(4-(2-NH2-6-Cl-Pym))-OH
EINECS	Contact for details

Quality Control

Our L-Phenylalanine derivative is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.