Description

tert-Butyl (1-(2-Methoxyethyl)-4-Oxo-4,5-Dihydro-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl)Methylcarbamate is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for oncology and anti-inflammatory drug candidates.
• Kinase Inhibitor Research: Serves as a core scaffold for the design and development of potent and selective kinase inhibitors, targeting various disease pathways.
• Process Chemistry & Scale-Up: Used in process research and development (PR&D) and pilot-scale manufacturing to optimize synthetic routes for new chemical entities (NCEs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic & Institutional Research: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	tert-Butyl (1-(2-Methoxyethyl)-4-Oxo-4,5-Dihydro-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl)Methylcarbamate
CAS No.	1033194-53-4
Molecular Formula	C14H21N5O4
Molecular Weight	323.35 g/mol
Synonyms	tert-Butyl N-[(1-(2-Methoxyethyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)methyl]carbamate; 6-[[(tert-Butoxycarbonyl)amino]methyl]-1-(2-methoxyethyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; BOC-protected Pyrazolopyrimidine Intermediate; 1-(2-Methoxyethyl)-6-((((tert-butoxy)carbonyl)amino)methyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one; tert-Butyl ((1-(2-Methoxyethyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl)methyl)carbamate
EINECS	Contact for details

Quality Control

Our production of tert-Butyl (1-(2-Methoxyethyl)-4-Oxo-4,5-Dihydro-1H-Pyrazolo[3,4-D]Pyrimidin-6-Yl)Methylcarbamate adheres to stringent quality management systems, ensuring batch-to-batch consistency for critical R&D and manufacturing applications. All material is released based on comprehensive analytical testing, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.