Description

2-Trifluoromethyl-Pyrimidine-5-Carbonitrile is a high-value fluorinated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its unique trifluoromethyl and nitrile functional groups make it a versatile intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily targeted at research and development teams in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for antiviral, anticancer, and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker due to its reactive nitrile group, useful for bioconjugation and target identification studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	2-Trifluoromethyl-Pyrimidine-5-Carbonitrile
CAS No.	1032229-36-9
Molecular Formula	C6H2F3N3
Molecular Weight	173.10 g/mol
Synonyms	5-Cyano-2-(trifluoromethyl)pyrimidine; 2-(Trifluoromethyl)pyrimidine-5-carbonitrile; Pyrimidine-5-carbonitrile, 2-(trifluoromethyl)-; 2-Trifluoromethyl-5-cyanopyrimidine
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-Pyrimidine-5-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.