Description

L-Naa Hcl CAS NO 1031799-40-2 is a high-purity, enantiomerically pure form of N-acetyl-L-aspartic acid hydrochloride, a derivative of the endogenous amino acid derivative N-acetylaspartate (NAA). This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its role as a specific precursor and biomarker. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, metabolic studies, and the synthesis of specialized peptides or prodrugs where chiral integrity is paramount.

Application

• Neuroscience Research: Used as a standard, precursor, or tracer in studies investigating N-acetylaspartate (NAA) metabolism, which is crucial for understanding conditions like Canavan disease, brain tumors, and mitochondrial disorders.
• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel therapeutic agents, particularly those targeting neurological pathways.
• Biochemical Standard: Employed as a high-purity reference standard in analytical methods such as HPLC, LC-MS, and NMR for quantifying NAA levels in biological samples.
• Metabolic Pathway Studies: Applied in in vitro and cell-based assays to elucidate the biosynthetic and catabolic pathways involving NAA in the central nervous system.
• Diagnostic Development: Potential use in the development of diagnostic kits or assays for neurological diseases where NAA is a biomarker.

Basic Information

Product Name	L-Naa Hcl
CAS No.	1031799-40-2
Molecular Formula	C6H9NO5 • HCl
Molecular Weight	211.60 g/mol
Synonyms	N-Acetyl-L-aspartic acid hydrochloride; (2S)-2-Acetamidobutanedioic acid hydrochloride; L-N-Acetylaspartic acid HCl; NAA-HCl; N-Acetyl-L-aspartate hydrochloride; N-Acetylaspartylglutamate precursor; N-Acetylaspartic acid (L-form) hydrochloride
EINECS	Contact for details

Quality Control

Our L-Naa Hcl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific data on identity, purity, and impurities is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a desiccated environment to prevent absorption of moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.