Description

3-Quinolinecarboxylic Acid, 7-(4-Acetyl-1-Piperazinyl)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-, (4-Chlorophenyl)Methyl Ester is a high-purity, advanced pharmaceutical intermediate designed for critical synthesis pathways. This compound is valued for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly within the fluoroquinolone antibiotic class. It is essential for research institutions and pharmaceutical manufacturers engaged in the synthesis and process development of next-generation antibacterial agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Used in research and development for creating new antibacterial compounds with targeted mechanisms of action.
• Process Chemistry & Scale-Up: Serves as a standard reference material for optimizing synthetic routes from laboratory to commercial production scale.
• Biochemical Research: Employed in studies investigating structure-activity relationships (SAR) of quinolone-based molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant API production.

Basic Information

Item	Details
Product Name	3-Quinolinecarboxylic Acid, 7-(4-Acetyl-1-Piperazinyl)-1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-, (4-Chlorophenyl)Methyl Ester
CAS No.	1031503-50-0
Molecular Formula	C26H25ClFN3O4
Molecular Weight	497.95 g/mol
Synonyms	7-(4-Acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (4-chlorobenzyl) ester; (4-Chlorobenzyl) 7-(4-acetylpiperazin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate; WCK 771 Intermediate; Levonadifloxacin Alalevonadifloxacin Intermediate; Benzenemethanol, 4-chloro-, 7-(4-acetyl-1-piperazinyl)-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate
EINECS	Contact for details

Quality Control

Our production of this pharmaceutical intermediate adheres to stringent quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting critical parameters such as assay and impurity profiles. We support development and commercial projects requiring material that meets ICH guidelines for impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.