Description

trans-4-[4-(7-Aminopyrazolo[1,5-A]Pyrimidin-6-Yl)Phenyl]Cyclohexaneacetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially in kinase inhibitor programs.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: May be utilized in the development of probes for studying specific biological pathways and target validation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with potential therapeutic value.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of pharmaceutical candidates.

Basic Information

Product Name	trans-4-[4-(7-Aminopyrazolo[1,5-A]Pyrimidin-6-Yl)Phenyl]Cyclohexaneacetic Acid
CAS No.	1031336-60-3
Molecular Formula	C20H22N4O2
Molecular Weight	350.42 g/mol
Synonyms	trans-4-[4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl]cyclohexaneacetic acid; 4-[4-(7-Amino-1H-pyrazolo[1,5-a]pyrimidin-6-yl)phenyl]cyclohexaneacetic acid (trans); 1031336-60-3; UNII-9F3Q6K7T0P; 9F3Q6K7T0P; CHEMBL3185222; AKOS025147064; trans-4-(4-(7-Aminopyrazolo[1,5-a]pyrimidin-6-yl)phenyl)cyclohexaneacetic acid
EINECS	Contact for details

Quality Control

Our trans-4-[4-(7-Aminopyrazolo[1,5-A]Pyrimidin-6-Yl)Phenyl]Cyclohexaneacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under inert atmosphere at -20°C. The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.