Description

Methanesulfonamide, n-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-Pyrimidinyl]-n-Methyl- is a high-purity, advanced pharmaceutical intermediate with a distinct pyrimidine core structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable functional groups.
• Fine Chemical Synthesis: Serves as a precursor for more complex molecules in custom synthesis and contract manufacturing.
• API Development: Employed in the research-scale and pilot-scale production of potential Active Pharmaceutical Ingredients.
• Biochemical Research: May be used as a tool compound or reference standard in biochemical assays and pharmacological studies.

Basic Information

Product Name	Methanesulfonamide, n-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-Pyrimidinyl]-n-Methyl-
CAS No.	1031246-43-1
Molecular Formula	C15H18FN3O2S
Molecular Weight	323.39 g/mol
Synonyms	N-Methyl-N-[4-(4-fluorophenyl)-6-(propan-2-yl)pyrimidin-2-yl]methanesulfonamide; 2-(N-Methylmethanesulfonamido)-4-(4-fluorophenyl)-6-isopropylpyrimidine; N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-methanesulfonamide; 1031246-43-1; Methanesulfonamide, N-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-pyrimidinyl]-N-methyl-
EINECS	Contact for details

Quality Control

Our Methanesulfonamide, n-[4-(4-Fluorophenyl)-6-(1-Methylethyl)-2-Pyrimidinyl]-n-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.