Description

2-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine is a high-purity, heterocyclic organic building block of significant importance in advanced chemical synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key scaffold for the synthesis of kinase inhibitors and other small-molecule therapeutic candidates targeting various diseases.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its fused bicyclic structure.
• Chemical Biology Probe Synthesis: Serves as a versatile building block for creating tool compounds to study biological pathways and protein function.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Used in university and government laboratories for fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	2-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine
CAS No.	1030377-43-5
Molecular Formula	C7H7ClN2
Molecular Weight	154.60 g/mol
Synonyms	2-Chloro-5,6-cyclopentenopyrimidine; 2-Chloro-6,7-dihydro-5H-cyclopentapyrimidine; 2-Chlorocyclopentapyrimidine; 5H-Cyclopenta[d]pyrimidine, 2-chloro-6,7-dihydro-; 1030377-43-5; 2-Chloro-6,7-dihydrocyclopenta[d]pyrimidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-6,7-dihydro-5H-cyclopenta[d]pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to cGMP principles and rigorous in-process controls guarantees a reliable supply of high-quality material for your most demanding synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.