Description

2-Fluoro-4-(Trifluoromethyl)Phenylhydrazine Hydrochloride is a high-purity, halogenated phenylhydrazine derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine-containing motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antiviral compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethyl and fluorine groups enhance biological activity and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reagent for bioconjugation and the synthesis of chemical probes to study enzyme mechanisms and protein interactions.
• Dye & Pigment Manufacturing: Acts as an intermediate for producing high-performance, light-fast azo dyes and functional pigments.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethyl)Phenylhydrazine Hydrochloride
CAS No.	1030313-53-1
Molecular Formula	C7H5F4N2·HCl
Molecular Weight	232.58 g/mol
Synonyms	1-(2-Fluoro-4-(trifluoromethyl)phenyl)hydrazine hydrochloride; [2-Fluoro-4-(trifluoromethyl)phenyl]hydrazine hydrochloride; 2-Fluoro-α,α,α-trifluoro-p-tolylhydrazine hydrochloride; 4-(Trifluoromethyl)-2-fluorophenylhydrazine hydrochloride; 2-Fluoro-4-trifluoromethylphenylhydrazine HCl; 2-Fluoro-4-(trifluoromethyl)aniline hydrochloride (common misnomer, verify structure); Hydrazine, [2-fluoro-4-(trifluoromethyl)phenyl]-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethyl)Phenylhydrazine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.