Description

2-[[1-(3-Chlorophenyl)-4-Oxo-5H-Pyrazolo[5,4-D]Pyrimidin-6-Yl]Sulfanyl]Propanamide is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of targeted small-molecule therapeutics, particularly kinase inhibitors. It is essential for research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs, especially those focused on oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Kinase Inhibitor Development: Serves as a core scaffold for research and production of potent and selective kinase inhibitors, a major class of oncology drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize drug candidate potency, selectivity, and pharmacokinetic properties.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP-scale production of clinical trial materials and commercial APIs.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening and biochemical assays.

Basic Information

Item	Details
Product Name	2-[[1-(3-Chlorophenyl)-4-Oxo-5H-Pyrazolo[5,4-D]Pyrimidin-6-Yl]Sulfanyl]Propanamide
CAS No.	1030203-81-6
Molecular Formula	C14H10ClN5O2S
Molecular Weight	347.78 g/mol
Synonyms	2-({[1-(3-Chlorophenyl)-4-oxo-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-6-yl]sulfanyl})propanamide; Propanamide, 2-[[1-(3-chlorophenyl)-4-oxo-5H-pyrazolo[5,4-d]pyrimidin-6-yl]thio]-; 1-(3-Chlorophenyl)-6-[(1-carbamoylethyl)sulfanyl]-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one; 1030203-81-6; Pyrazolo[5,4-d]pyrimidine intermediate; Kinase inhibitor intermediate
EINECS	Contact for details

Quality Control

Our 2-[[1-(3-Chlorophenyl)-4-Oxo-5H-Pyrazolo[5,4-D]Pyrimidin-6-Yl]Sulfanyl]Propanamide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and detailed Certificates of Analysis (COA) to support your regulatory filings and ensure consistent quality and supply reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.