Description

5-Bromo-2-Piperazin-1-Ylpyrimidine Hydrochloride is a high-purity pharmaceutical intermediate and building block of significant importance in modern organic synthesis. Its core value lies in its role as a versatile precursor for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-quality building blocks for drug discovery and scale-up.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Research: Serves as a key scaffold for developing chemical probes to study biological pathways and protein function.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary molecules for client-specific applications.

Basic Information

Product Name	5-Bromo-2-Piperazin-1-Ylpyrimidine Hydrochloride
CAS No.	1030022-85-5
Molecular Formula	C8H11BrClN5
Molecular Weight	292.57 g/mol
Synonyms	5-Bromo-2-(piperazin-1-yl)pyrimidine hydrochloride; 2-(1-Piperazinyl)-5-bromopyrimidine hydrochloride; 5-Bromo-2-piperazin-1-yl-pyrimidine HCl; 5-Bromo-2-(1-piperazinyl)pyrimidine monohydrochloride; 1030022-85-5; 5-Br-2-PP HCl
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Piperazin-1-Ylpyrimidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.