Description

Ac-D-5-Methoxytryptophan is a chemically modified derivative of the essential amino acid tryptophan, featuring acetylation and a methoxy substitution. This specific enantiomer is a critical chiral building block and intermediate in advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutics and conducting proteomics studies.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a specialized reagent in proteomics, enzyme studies, and metabolic pathway analysis.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis for research and development.
• Neurology & Psychiatry Research: Investigated for its role as a precursor or analog in studies related to serotonin and melatonin pathways.
• Standards & Reference Materials: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ac-D-5-Methoxytryptophan
CAS No.	1029430-13-4
Molecular Formula	C₁₄H₁₆N₂O₄
Molecular Weight	276.29 g/mol
Synonyms	N-Acetyl-D-5-methoxytryptophan; Ac-D-5-MOTrp; (R)-2-Acetamido-3-(5-methoxy-1H-indol-3-yl)propanoic acid; D-5-Methoxy-N-acetyltryptophan; N-Acetyl-5-methoxy-D-tryptophan; 5-Methoxy-D-tryptophan, N-acetyl-; Ac-D-5-MeOTry
EINECS	Contact for details

Quality Control

Our Ac-D-5-Methoxytryptophan is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.