Description

1-Cyclopropyl-8-Ethoxy-6-Fluoro-7-[(4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate of significant importance in modern medicinal chemistry. This compound is a key synthetic precursor in the development of novel antibacterial agents, particularly within the fluoroquinolone class. It is essential for research and development laboratories, process chemists, and manufacturers in the global pharmaceutical industry seeking to develop next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel fluoroquinolone antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Used in R&D for creating new antibacterial compounds with potentially improved efficacy and spectrum.
• Process Chemistry & Scale-Up: Serves as a key material for optimizing synthetic routes and scaling production from laboratory to commercial batches.
• Reference Standard: Employed as an analytical standard for quality control and method validation in API manufacturing.
• Medicinal Chemistry Research: Utilized in structure-activity relationship (SAR) studies to explore new chemical entities for antibacterial activity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific drug development projects.

Basic Information

Product Name	1-Cyclopropyl-8-Ethoxy-6-Fluoro-7-[(4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
CAS No.	1029364-75-7
Molecular Formula	C22H26FN3O4
Molecular Weight	415.46 g/mol
Synonyms	1-Cyclopropyl-8-ethoxy-6-fluoro-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; (4aR,7aR)-1-Cyclopropyl-8-ethoxy-6-fluoro-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Fluoroquinolone Intermediate; Antibacterial Intermediate; CAS 1029364-75-7
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-8-Ethoxy-6-Fluoro-7-[(4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.