Description

1-Cyclopropyl-1,4-Dihydro-6,8-Dimethoxy-7-[(4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of antibacterial and antiviral pharmaceuticals. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Antiviral Drug Research: Used in the development of new chemical entities targeting viral DNA gyrase and topoisomerase enzymes.
• Process Chemistry: Serves as a critical intermediate in scale-up and optimization studies for API manufacturing routes.
• Biochemical Research: Employed in enzymatic and receptor-binding studies to investigate mechanisms of action.
• Reference Standard: Utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Academic Research: Used in university and institutional labs for medicinal chemistry projects and structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-Cyclopropyl-1,4-Dihydro-6,8-Dimethoxy-7-[(4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid
CAS No.	1029364-73-5
Molecular Formula	C22H27N3O5
Molecular Weight	413.47 g/mol
Synonyms	7-[(4aR,7aR)-Octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-1-cyclopropyl-6,8-dimethoxy-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; (4aR,7aR)-7-(Octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-1-cyclopropyl-6,8-dimethoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-6,8-dimethoxy-7-[(4aR,7aR)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; Quinolonecarboxylic Acid Derivative; GSK-1 Intermediate; Antibacterial Intermediate CAS 1029364-73-5
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-1,4-Dihydro-6,8-Dimethoxy-7-[(4As,7As)-Octahydro-6H-Pyrrolo[3,4-B]Pyridin-6-Yl]-4-Oxo-3-Quinolinecarboxylic Acid is manufactured under strict quality management systems. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. Production can adhere to cGMP guidelines for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.