Description

(3S)-3-Amino-3-(3-Fluoro-4-Hydroxyphenyl)Propanoic Acid is a high-purity, non-natural amino acid derivative featuring a chiral center and a fluorinated aromatic ring, making it a critical building block for advanced pharmaceutical synthesis. Its unique structure provides a versatile scaffold for medicinal chemistry, enabling the development of targeted therapeutics with enhanced metabolic stability and binding affinity. This compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly for creating novel enzyme inhibitors, peptide mimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for central nervous system (CNS) and metabolic disorder targets.
• Peptidomimetics Development: Used to incorporate fluorinated tyrosine analogs into peptide chains to enhance stability, bioavailability, and receptor selectivity.
• Enzyme Inhibitor Research: Serves as a core structure for designing potent and selective inhibitors of kinases, proteases, and other enzymes.
• Chemical Biology Probes: Employed in the creation of fluorescent or affinity-labeled probes for studying protein function and interaction.
• Agrochemical Research: Potential intermediate for developing advanced, bioactive compounds with improved environmental profiles.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting research in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	(3S)-3-Amino-3-(3-Fluoro-4-Hydroxyphenyl)Propanoic Acid
CAS No.	1027335-64-3
Molecular Formula	C9H10FNO3
Molecular Weight	199.18 g/mol
Synonyms	(S)-3-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoic acid; (3S)-3-Amino-3-(3-fluoro-4-hydroxyphenyl)propionic acid; β-Amino-β-(3-fluoro-4-hydroxyphenyl)propionic acid, (S)-; 3-Fluoro-L-tyrosine derivative; (S)-3-Amino-3-(3-fluoro-4-hydroxy-phenyl)-propionic acid; 1027335-64-3; (S)-3-Amino-3-(3-fluoro-4-hydroxyphenyl)propanoate
EINECS	Contact for details

Quality Control

Our (3S)-3-Amino-3-(3-Fluoro-4-Hydroxyphenyl)Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.