Description

2,3-Difluoro-4-Iodoaniline is a versatile halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and iodine atoms on the aromatic ring, which allows for precise structural modifications and the introduction of unique electronic properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for fluorinated drug candidates targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing aromatic diamines and other monomers used in high-performance electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling the construction of complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new reaction pathways, creating specialized ligands, and developing novel fluorinated compounds.
• Material Science: Utilized in the synthesis of specialized polymers, dyes, and pigments where halogen atoms impart specific durability and performance characteristics.

Basic Information

Product Name	2,3-Difluoro-4-Iodoaniline
CAS No.	1026989-94-5
Molecular Formula	C6H4F2IN
Molecular Weight	255.01 g/mol
Synonyms	4-Iodo-2,3-difluoroaniline; 2,3-Difluoro-4-iodobenzenamine; Benzenamine, 2,3-difluoro-4-iodo-; 2,3-Difluoro-4-iodophenylamine; 4-Amino-2,3-difluoro-1-iodobenzene; 2,3-DFIA
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-4-Iodoaniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.